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Livres
Articles (47)
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Spectroscopic studies of molybdenum and tungsten enzymes

M. Jake Pushie, Graham N. George

Journal:

Coordination Chemistry Reviews

Année:

2011

Langue:

english

Fichier:

PDF, 3.24 MB

english, 2011

Elemental and Chemically Specific X-ray Fluorescence Imaging of Biological Systems

Pushie, M. Jake, Pickering, Ingrid J., Korbas, Malgorzata, Hackett, Mark J., George, Graham N.

Journal:

Chemical Reviews

Année:

2014

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2014

Towards a custom chelator for mercury: evaluation of coordination environments by molecular modeling

Juxia Fu, Ruth E. Hoffmeyer, M. Jake Pushie, Satya P. Singh, Ingrid J. Pickering, Graham N. George

Journal:

JBIC Journal of Biological Inorganic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 636 KB

english, 2011

Can copper binding to the prion protein generate a misfolded form of the protein?

M. Jake Pushie, Arvi Rauk, Frank R. Jirik, Hans J. Vogel

Journal:

BioMetals

Année:

2009

Langue:

english

Fichier:

PDF, 620 KB

english, 2009

Computational studies of Cu(II)[peptide] binding motifs: Cu[HGGG] and Cu[HG] as models for Cu(II) binding to the prion protein octarepeat region

Pushie, Jake, Rauk, Arvi

Journal:

JBIC Journal of Biological Inorganic Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 716 KB

english, 2003

The fictile coordination chemistry of cuprous-thiolate sites in copper chaperones

M. Jake Pushie, Limei Zhang, Ingrid J. Pickering, Graham N. George

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2012

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2012

Metalloprotein active site structure determination: Synergy between X-ray absorption spectroscopy and X-ray crystallography

Julien J.H. Cotelesage, M. Jake Pushie, Pawel Grochulski, Ingrid J. Pickering, Graham N. George

Journal:

Journal of Inorganic Biochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2012

X-ray-induced photo-chemistry and X-ray absorption spectroscopy of biological samples

George, Graham N., Pickering, Ingrid J., Pushie, M. Jake, Nienaber, Kurt, Hackett, Mark J., Ascone, Isabella, Hedman, Britt, Hodgson, Keith O., Aitken, Jade B., Levina, Aviva, Glover, Christopher, Lay

Journal:

Journal of Synchrotron Radiation

Année:

2012

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2012

Molecular Dynamics Simulations of Two Tandem Octarepeats from the Mammalian Prion Protein: Fully Cu2+-bound and Metal-Free Forms

Pushie, M. Jake, Vogel, Hans J.

Journal:

Biophysical Journal

Année:

2007

Langue:

english

Fichier:

PDF, 883 KB

english, 2007

Modeling by Assembly and Molecular Dynamics Simulations of the Low Cu2+ Occupancy Form of the Mammalian Prion Protein Octarepeat Region: Gaining Insight into Cu2+-Mediated β-Cleavage

Pushie, M. Jake, Vogel, Hans J.

Journal:

Biophysical Journal

Année:

2008

Langue:

english

Fichier:

PDF, 596 KB

english, 2008

X-ray Absorption Spectroscopy of a Quantitatively Mo(V) Dimethyl Sulfoxide Reductase Species

Pushie, M. Jake, Cotelesage, Julien J. H., Lyashenko, Ganna, Hille, Russ, George, Graham N.

Journal:

Inorganic Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2013

Nature of Halide Binding to the Molybdenum Site of Sulfite Oxidase

Pushie, M. Jake, Doonan, Christian J., Wilson, Heather L., Rajagopalan, K. V., George, Graham. N.

Journal:

Inorganic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.48 MB

english, 2011

New Insights into Metal Interactions with the Prion Protein: EXAFS Analysis and Structure Calculations of Copper Binding to a Single Octarepeat from the Prion Protein

McDonald, Alex, Pushie, M. Jake, Millhauser, Glenn L., George, Graham N.

Journal:

Journal of Physical Chemistry B

Année:

2013

Langue:

english

Fichier:

PDF, 2.82 MB

english, 2013

The solution structure of the copper clioquinol complex

Pushie, M. Jake, Nienaber, Kurt H., Summers, Kelly L., Cotelesage, Julien J.H., Ponomarenko, Olena, Nichol, Helen K., Pickering, Ingrid J., George, Graham N.

Journal:

Journal of Inorganic Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 745 KB

english, 2014

Active-Site Dynamics and Large-Scale Domain Motions of Sulfite Oxidase: A Molecular Dynamics Study

Pushie, M. Jake, George, Graham N.

Journal:

Journal of Physical Chemistry B

Année:

2010

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2010

The Structures of the C185S and C185A Mutants of Sulfite Oxidase Reveal Rearrangement of the Active Site

Qiu, James A., Wilson, Heather L., Pushie, M. Jake, Kisker, Caroline, George, Graham N., Rajagopalan, K. V.

Journal:

Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 3.75 MB

english, 2010

Molybdenum Site Structure of Escherichia coli YedY, a Novel Bacterial Oxidoreductase

Pushie, M. Jake, Doonan, Christian J., Moquin, Kamila, Weiner, Joel H., Rothery, Richard, George, Graham N.

Journal:

Inorganic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.70 MB

english, 2011

Mass Spectrometric Determination of the Coordination Geometry of Potential Copper(II) Surrogates for the Mammalian Prion Protein Octarepeat Region

Pushie, M. Jake, Ross, Andrew R. S., Vogel, Hans J.

Journal:

Analytical Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 391 KB

english, 2007

Prion protein expression level alters regional copper, iron and zinc content in the mouse brain

Pushie, M. Jake, Pickering, Ingrid J., Martin, Gary R., Tsutsui, Shigeki, Jirik, Frank R., George, Graham N.

Journal:

Metallomics

Année:

2011

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2011

The affinity of HGGG, GHGG, GGHG, and GGGH peptides for copper(II) and the structures of their complexes — An ab initio study 1

Barry, Stephen D., Rickard, Gail A., Pushie, M. Jake, Rauk, Arvi

Journal:

Canadian Journal of Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2009

A Potential Mechanism for Cu 2+ Reduction, β-Cleavage, and β-Sheet Initiation Within The N-Terminal Domain of the Prion Protein: Insights from Density Functional Theory and Molecular Dynamics Calculations

Pushie, M. Jake, Vogel, Hans J.

Journal:

Journal of Toxicology and Environmental Health

Année:

2009

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2009

Combined EXAFS and DFT Structure Calculations Provide Structural Insights into the 1:1 Multi-Histidine Complexes of Cu II , Cu I , and Zn II with the Tandem Octarepeats of the Mammalian Prion Protein

Pushie, M. Jake, Nienaber, Kurt H., McDonald, Alex, Millhauser, Glenn L., George, Graham N.

Journal:

Chemistry - A European Journal

Année:

2014

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2014

An NMR Metabolomics Study of Elk Inoculated with Chronic Wasting Disease

Pushie, M. Jake, Shaykhutdinov, Rustem, Nazyrova, Alsu, Graham, Catherine, Vogel, Hans J.

Journal:

Journal of Toxicology and Environmental Health

Année:

2011

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2011

Model Peptide Studies Reveal a Mixed Histidine-Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1

Pushie, M. Jake, Shaw, Katharine, Franz, Katherine J., Shearer, Jason, Haas, Kathryn L.

Journal:

Inorganic Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2015

Interaction between Prion Protein's Copper-Bound Octarepeat Domain and a Charged C-Terminal Pocket Suggests a Mechanism for N-Terminal Regulation

Evans, Eric G.B., Pushie, M. Jake, Markham, Kate A., Lee, Hsiau-Wei, Millhauser, Glenn L.

Journal:

Structure

Année:

2016

Langue:

english

Fichier:

PDF, 2.65 MB

english, 2016

Trifluoroselenomethionine - a New Non-Natural Amino Acid

Block, Eric, Booker, Squire, Flores-Penalba, Sonia, George, Graham, Gundala, Sivaji, Landgraf, Brad, Liu, Jun, Lodge, Stephene, Pushie, Jake, Rozovsky, Sharon, Vattekkatte, Abith, Yaghi, Rama, Zeng, H

Journal:

ChemBioChem

Année:

2016

Langue:

english

Fichier:

PDF, 2.44 MB

english, 2016

Insights into the Nature of the Chemical Bonding in Thiophene-2-thiol from X-ray Absorption Spectroscopy

Cotelesage, Julien J. H., Pushie, M. Jake, Vogt, Linda, Barney, Monica, Nissan, Andrew, Pickering, Ingrid J., George, Graham N.

Journal:

Journal of Physical Chemistry A

Année:

2016

Langue:

english

Fichier:

PDF, 758 KB

english, 2016

Chemical Sensitivity of the Sulfur K-Edge X-ray Absorption Spectra of Organic Disulfides

Pickering, Ingrid J., Barney, Monica M, Cotelesage, Julien J.H., Vogt, Linda, Pushie, Michael Jake, Nissan, Andrew, Prince, Roger C., George, Graham N.

Journal:

Journal of Physical Chemistry A

Année:

2016

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2016

Insect excretes unusual six-coordinate pentavalent arsenic species

Andrahennadi, Ruwandi, Fu, Juxia, Pushie, M. Jake, Wiramanaden, Cheryl I. E., George, Graham N., Pickering, Ingrid J.

Journal:

Environmental Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 376 KB

english, 2009

Concurrent Glycogen and Lactate Imaging with FTIR Spectroscopy to Spatially Localize Metabolic Parameters of the Glial Response following Brain Ischemia

Hackett, Mark John, Sylvain, Nicole J, Hou, Huishu, Caine, Sally, Alaverdashvili, Mariam, Pushie, Michael Jake, Kelly, Michael E

Journal:

Analytical Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2016

The active site structure and catalytic mechanism of arsenite oxidase

Warelow, Thomas P., Pushie, M. Jake, Cotelesage, Julien J. H., Santini, Joanne M., George, Graham N.

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 2.58 MB

english, 2017

Structure and Affinity of Cu(I) Bound to Human Serum Albumin

Sendzik, Madison, Pushie, M. Jake, Stefaniak, Ewelina, Haas, Kathryn L.

Journal:

Inorganic Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2017

Cryoprotectants Severely Exacerbate X-ray Induced Photoreduction

Nienaber, Kurt H., Pushie, M. Jake, Cotelesage, Julien J.H., Pickering, Ingrid J., George, Graham N.

Journal:

The Journal of Physical Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 361 KB

english, 2018

Revealing the penumbra through imaging elemental markers of cellular metabolism in an ischemic stroke model

Pushie, M. Jake, Crawford, Andrew, Sylvain, Nicole J, Hou, Huishu, Hackett, Mark J., George, Graham N., Kelly, Michael E

Journal:

ACS Chemical Neuroscience

Année:

2018

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2018

Comment on “Insights into the Nature of the Chemical Bonding in Thiophene-2-thiol from X-ray Absorption Spectroscopy”

Pushie, M. Jake, Cotelesage, Julien J. H., Vogt, Linda, Barney, Monica, Pickering, Ingrid J., George, Graham N.

Journal:

Journal of Physical Chemistry A

Année:

2018

Langue:

english

Fichier:

PDF, 621 KB

english, 2018

Direct Label-Free Imaging of Brain Tissue using Synchrotron Light: A Review of New Spectroscopic Tools for the Modern Neuroscientist

Pushie, M. Jake, Kelly, Michael E, Hackett, Mark

Journal:

The Analyst (Royal Society of Chemistry)

Année:

2018

Langue:

english

Fichier:

PDF, 2.58 MB

english, 2018

Mapping Alterations to the Endogenous Elemental Distribution within the Lateral Ventricles and Choroid Plexus in Brain Disorders Using X-Ray Fluorescence Imaging

Lins, Brittney R., Pushie, Jake M., Jones, Michael, Howard, Daryl L., Howland, John G., Hackett, Mark J., Rozhkova, Elena A.

Journal:

PLoS ONE

Année:

2016

Langue:

english

Fichier:

PDF, 6.53 MB

english, 2016

A comparison of parametric and integrative approaches for X-ray fluorescence analysis applied to a Stroke model

Crawford, Andrew M., Sylvain, Nicole J., Hou, Huishu, Hackett, Mark J., Pushie, M. Jake, Pickering, Ingrid J., George, Graham N., Kelly, Mike E.

Journal:

Journal of Synchrotron Radiation

Année:

2018

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2018

Altered Domain Structure of the Prion Protein Caused by Cu2+ Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR

McDonald, Alex J., Leon, Deborah R., Markham, Kathleen A., Wu, Bei, Heckendorf, Christian F., Schilling, Kevin, Showalter, Hollis D., Andrews, Philip C., McComb, Mark E., Pushie, M. Jake, Costello, Ca

Journal:

Structure

Année:

2019

Langue:

english

Fichier:

PDF, 4.45 MB

english, 2019

Using N-Terminal Coordination of Cu(II) and Ni(II) to Isolate the Coordination Environment of Cu(I) and Cu(II) Bound to His13 and His14 in Amyloid-β(4–16)

Pushie, M. Jake, Stefaniak, Ewelina, Sendzik, Madison R., Sokaras, Dimosthenis, Kroll, Thomas, Haas, Kathryn L.

Journal:

Inorganic Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 6.72 MB

english, 2019

Using N-Terminal Coordination of Cu(II) and Ni(II) to Isolate the Coordination Environment of Cu(I) and Cu(II) Bound to His13 and His14 in Amyloid-β(4–16)

Pushie, M. Jake, Stefaniak, Ewelina, Sendzik, Madison R., Sokaras, Dimosthenis, Kroll, Thomas, Haas, Kathryn L.

Journal:

Inorganic Chemistry

Année:

2019

Fichier:

PDF, 6.72 MB

2019

A Review of ex vivo Elemental Mapping Methods to Directly Image Changes in the Homeostasis of Diffusible Ions (Na+, K+, Mg2 +, Ca2 +, Clâ) Within Brain Tissue

Hartnell, David, Andrews, Wendy, Smith, Nicole, Jiang, Haibo, McAllum, Erin, Rajan, Ramesh, Colbourne, Frederick, Fitzgerald, Melinda, Lam, Virginie, Takechi, Ryusuke, Pushie, M. Jake, Kelly, Michael

Journal:

Frontiers in Neuroscience

Année:

2020

Fichier:

PDF, 2.78 MB

2020

Imaging Lipophilic Regions in Rodent Brain Tissue with Halogenated BODIPY Probes

Hartnell, David, Schwehr, Bradley, Gillespie-Jones, Kate, Alwis, Dasuni, Rajan, Ramesh, Hou, Huishu, sylvain, nicole j, Pushie, M. Jake Jake, Kelly, Michael E, Massi, Massimiliano, Hackett, Mark

Journal:

The Analyst (Royal Society of Chemistry)

Année:

2020

Fichier:

PDF, 1.35 MB

2020

Both N-Terminal and C-Terminal Histidine Residues of the Prion Protein are Essential for Copper Coordination and Neuroprotective Self-Regulation

Schilling, Kevin M., Tao, Lizhi, Wu, Bei, Kiblen, Joseph T.M., Ubilla-Rodriguez, Natalia C., Pushie, M. Jake, Britt, R. David, Roseman, Graham P., Harris, David A., Millhauser, Glenn L.

Journal:

Journal of Molecular Biology

Année:

2020

Fichier:

PDF, 13.31 MB

2020

Sample preparation with sucrose cryoprotection dramatically alters Zn distribution in the rodent hippocampus, as revealed by elemental mapping

Pushie, M. Jake Jake, Hollings, Ashley, Reinhardt, Juliane, Webb, Samuel M, Lam, Virginie, Takechi, Ryu, Mamo, J.C.L., Paterson, Phyllis, Kelly, Michael E, George, Graham Neil, Pickering, Ingrid, Hack

Journal:

Journal of Analytical Atomic Spectrometry

Année:

2020

Fichier:

PDF, 3.13 MB

2020

Solution Chemistry of Copper(II) Binding to Substituted 8-Hydroxyquinolines

Summers, Kelly L., Pushie, M. Jake, Sopasis, George J., James, Ashley K., Dolgova, Natalia V., Sokaras, Dimosthenis, Kroll, Thomas, Harris, Hugh H., Pickering, Ingrid J., George, Graham N.

Journal:

Inorganic Chemistry

Année:

2020

Fichier:

PDF, 3.22 MB

2020

Exploration of the Potential Role for AÎ² in Delivery of Extracellular Copper to Ctr1

Stefaniak, Ewelina, Pushie, M. Jake, Vaerewyck, Catherine, Corcelli, David, Griggs, Chloe, Lewis, Whitney, Kelley, Emma, Maloney, Noreen, Sendzik, Madison, Bal, Wojciech, Haas, Kathryn L.

Journal:

Inorganic Chemistry

Année:

2020

Fichier:

PDF, 6.42 MB

2020